Evidence for decreasing sperm count in African population from 1965 to 2015
Purpose: This meta-analysis, following our previous reports those documented an overall 57% diminution in mean sperm concentration around the globe over past 35 years and 32.5% decline in past 50 years in European population, attempts to report the declining trend of sperm concentrations in African...
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| Vydané v: | African health sciences Ročník 17; číslo 2; s. 418 - 427 |
|---|---|
| Hlavní autori: | , , , , |
| Médium: | Journal Article |
| Jazyk: | English |
| Vydavateľské údaje: |
Uganda
Makerere University Medical School
01.06.2017
Makerere Medical School |
| Predmet: | |
| ISSN: | 1680-6905, 1729-0503, 1680-6905, 1729-0503 |
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| Abstract | Purpose: This meta-analysis, following our previous reports those
documented an overall 57% diminution in mean sperm concentration around
the globe over past 35 years and 32.5% decline in past 50 years in
European population, attempts to report the declining trend of sperm
concentrations in African population between 1965 and 2015. Methods: In
the course of retrieval of data following MOOSE guidelines and PRISMA
checklist, we found a total of fourteen studies that have been
conducted during that period on altering sperm concentration in the
African male. Results: Following analysis of the data, a time-dependent
decline of sperm concentration (r = -0.597, p = 0.02) and an overall
72.6% decrease in mean sperm concentration was noted in the past 50
years. The major matter of concern is the present mean concentration
(20.38×106/ml) is very near to WHO cut-off value of 2010 of
15×106/ml. Several epidemic diseases, genital tract infection,
pesticides and heavy metal toxicity, regular consumption of tobacco and
alcohol are reported as predominant causative factors. Conclusion: This
comprehensive, evidence-based meta-analysis and systematic review
concisely presents the evidence of decreased sperm concentration in the
African male over past 50 years with possible causative factors to
serve the scientific research zone related to male reproductive health. |
|---|---|
| AbstractList | This meta-analysis, following our previous reports those documented an overall 57% diminution in mean sperm concentration around the globe over past 35 years and 32.5% decline in past 50 years in European population, attempts to report the declining trend of sperm concentrations in African population between 1965 and 2015. This meta-analysis, following our previous reports those documented an overall 57% diminution in mean sperm concentration around the globe over past 35 years and 32.5% decline in past 50 years in European population, attempts to report the declining trend of sperm concentrations in African population between 1965 and 2015.PURPOSEThis meta-analysis, following our previous reports those documented an overall 57% diminution in mean sperm concentration around the globe over past 35 years and 32.5% decline in past 50 years in European population, attempts to report the declining trend of sperm concentrations in African population between 1965 and 2015.In the course of retrieval of data following MOOSE guidelines and PRISMA checklist, we found a total of fourteen studies that have been conducted during that period on altering sperm concentration in the African male.METHODSIn the course of retrieval of data following MOOSE guidelines and PRISMA checklist, we found a total of fourteen studies that have been conducted during that period on altering sperm concentration in the African male.Following analysis of the data, a time-dependent decline of sperm concentration (r = -0.597, p = 0.02) and an overall 72.6% decrease in mean sperm concentration was noted in the past 50 years. The major matter of concern is the present mean concentration (20.38×106/ml) is very near to WHO cut-off value of 2010 of 15×106/ml. Several epidemic diseases, genital tract infection, pesticides and heavy metal toxicity, regular consumption of tobacco and alcohol are reported as predominant causative factors.RESULTSFollowing analysis of the data, a time-dependent decline of sperm concentration (r = -0.597, p = 0.02) and an overall 72.6% decrease in mean sperm concentration was noted in the past 50 years. The major matter of concern is the present mean concentration (20.38×106/ml) is very near to WHO cut-off value of 2010 of 15×106/ml. Several epidemic diseases, genital tract infection, pesticides and heavy metal toxicity, regular consumption of tobacco and alcohol are reported as predominant causative factors.This comprehensive, evidence-based meta-analysis and systematic review concisely presents the evidence of decreased sperm concentration in the African male over past 50 years with possible causative factors to serve the scientific research zone related to male reproductive health.CONCLUSIONThis comprehensive, evidence-based meta-analysis and systematic review concisely presents the evidence of decreased sperm concentration in the African male over past 50 years with possible causative factors to serve the scientific research zone related to male reproductive health. This meta-analysis, following our previous reports those documented an overall 57% diminution in mean sperm concentration around the globe over past 35 years and 32.5% decline in past 50 years in European population, attempts to report the declining trend of sperm concentrations in African population between 1965 and 2015. In the course of retrieval of data following MOOSE guidelines and PRISMA checklist, we found a total of fourteen studies that have been conducted during that period on altering sperm concentration in the African male. Following analysis of the data, a time-dependent decline of sperm concentration (r = -0.597, p = 0.02) and an overall 72.6% decrease in mean sperm concentration was noted in the past 50 years. The major matter of concern is the present mean concentration (20.38×106/ml) is very near to WHO cut-off value of 2010 of 15×106/ml. Several epidemic diseases, genital tract infection, pesticides and heavy metal toxicity, regular consumption of tobacco and alcohol are reported as predominant causative factors. This comprehensive, evidence-based meta-analysis and systematic review concisely presents the evidence of decreased sperm concentration in the African male over past 50 years with possible causative factors to serve the scientific research zone related to male reproductive health. Purpose: This meta-analysis, following our previous reports those documented an overall 57% diminution in mean sperm concentration around the globe over past 35 years and 32.5% decline in past 50 years in European population, attempts to report the declining trend of sperm concentrations in African population between 1965 and 2015. Methods: In the course of retrieval of data following MOOSE guidelines and PRISMA checklist, we found a total of fourteen studies that have been conducted during that period on altering sperm concentration in the African male. Results: Following analysis of the data, a time-dependent decline of sperm concentration (r = -0.597, p = 0.02) and an overall 72.6% decrease in mean sperm concentration was noted in the past 50 years. The major matter of concern is the present mean concentration (20.38×106/ml) is very near to WHO cut-off value of 2010 of 15×106/ml. Several epidemic diseases, genital tract infection, pesticides and heavy metal toxicity, regular consumption of tobacco and alcohol are reported as predominant causative factors. Conclusion: This comprehensive, evidence-based meta-analysis and systematic review concisely presents the evidence of decreased sperm concentration in the African male over past 50 years with possible causative factors to serve the scientific research zone related to male reproductive health. |
| Author | Sengupta, Pallav Krajewska-Kulak, Elzbieta Nwagha, Uchenna Dutta, Sulagna Izuka, Emmanuel |
| AuthorAffiliation | 3 Integrated Medical Care, Medical University of Bialystok, Bialystok, Poland 2 Department of of Physiology, Obstetrics and Gynecology, College of Medicine, University of Nigeria, Enugu Campus, Nigeria 4 Department of Obstetrics and Gynecology, College of Medicine, University of Nigeria, Enugu Campus, Nigeria 1 Physiology, Lincoln University College, Petaling Jaya, Malaysia |
| AuthorAffiliation_xml | – name: 4 Department of Obstetrics and Gynecology, College of Medicine, University of Nigeria, Enugu Campus, Nigeria – name: 1 Physiology, Lincoln University College, Petaling Jaya, Malaysia – name: 2 Department of of Physiology, Obstetrics and Gynecology, College of Medicine, University of Nigeria, Enugu Campus, Nigeria – name: 3 Integrated Medical Care, Medical University of Bialystok, Bialystok, Poland |
| Author_xml | – sequence: 1 fullname: Sengupta, Pallav – sequence: 2 fullname: Nwagha, Uchenna – sequence: 3 fullname: Dutta, Sulagna – sequence: 4 fullname: Krajewska-Kulak, Elzbieta – sequence: 5 fullname: Izuka, Emmanuel |
| BackLink | https://www.ncbi.nlm.nih.gov/pubmed/29062337$$D View this record in MEDLINE/PubMed |
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| Snippet | Purpose: This meta-analysis, following our previous reports those
documented an overall 57% diminution in mean sperm concentration around
the globe over past... This meta-analysis, following our previous reports those documented an overall 57% diminution in mean sperm concentration around the globe over past 35 years... |
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| SubjectTerms | Adult Africa Africa - epidemiology Body fluids Humans Male Mental health Middle Aged Reproductive health Research methodology Risk Factors Semen quality sperm concentration sperm count Sperm Count - statistics & numerical data Young Adult |
| Title | Evidence for decreasing sperm count in African population from 1965 to 2015 |
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