Hepatitis D virus in 2021: virology, immunology and new treatment approaches for a difficult-to-treat disease

Approximately 5% of individuals infected with hepatitis B virus (HBV) are coinfected with hepatitis D virus (HDV). Chronic HBV/HDV coinfection is associated with an unfavourable outcome, with many patients developing liver cirrhosis, liver failure and eventually hepatocellular carcinoma within 5–10...

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Bibliographic Details
Published in:	Gut Vol. 70; no. 9; pp. 1782 - 1794
Main Authors:	Urban, Stephan, Neumann-Haefelin, Christoph, Lampertico, Pietro
Format:	Journal Article
Language:	English
Published:	England BMJ Publishing Group LTD 01.09.2021 BMJ Publishing Group
Subjects:	Adaptive Immunity Animal models Animals Antigens Antiviral agents Antiviral drugs CD4 antigen CD8 antigen Cell division Cirrhosis Clinical trials Drug development Epitopes Genomes Genotype & phenotype Hepatitis B Hepatitis B surface antigen Hepatitis D - immunology Hepatitis D - therapy Hepatitis D - virology Hepatitis D, Chronic - immunology Hepatitis D, Chronic - therapy Hepatitis D, Chronic - virology Hepatitis delta virus Hepatitis Delta Virus - genetics Hepatitis Delta Virus - immunology Hepatocellular carcinoma Humans Immunity, Innate Immunology Infections Life cycles Liver cancer Liver cirrhosis Liver diseases Liver failure Liver transplants Lymphocytes T Patients Polymers Polypeptides Proteins Recent Advances in Clinical Practice Response rates Virology Viruses α-Interferon chronic viral hepatitis immunology in hepatology antiviral therapy hepatitis D
ISSN:	0017-5749, 1468-3288, 1468-3288
Online Access:	Get full text
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