Benefits and harms of drug treatment for type 2 diabetes: systematic review and network meta-analysis of randomised controlled trials

AbstractObjectiveTo compare the benefits and harms of drug treatments for adults with type 2 diabetes, adding non-steroidal mineralocorticoid receptor antagonists (including finerenone) and tirzepatide (a dual glucose dependent insulinotropic polypeptide (GIP)/glucagon-like peptide-1 (GLP-1) recepto...

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Bibliographic Details
Published in:	BMJ (Online) Vol. 381; p. e074068
Main Authors:	Shi, Qingyang, Nong, Kailei, Vandvik, Per Olav, Guyatt, Gordon H, Schnell, Oliver, Rydén, Lars, Marx, Nikolaus, Brosius, Frank C, Mustafa, Reem A, Agarwal, Arnav, Zou, Xinyu, Mao, Yunhe, Asadollahifar, Aminreza, Chowdhury, Saifur Rahman, Zhai, Chunjuan, Gupta, Sana, Gao, Ya, Lima, João Pedro, Numata, Kenji, Qiao, Zhi, Fan, Qinlin, Yang, Qinbo, Jin, Yinghui, Ge, Long, Yang, Qiuyu, Zhu, Hongfei, Yang, Fan, Chen, Zhe, Lu, Xi, He, Siyu, Chen, Xiangyang, Lyu, Xiafei, An, Xingxing, Chen, Yaolong, Hao, Qiukui, Standl, Eberhard, Siemieniuk, Reed, Agoritsas, Thomas, Tian, Haoming, Li, Sheyu
Format:	Journal Article
Language:	English
Published:	England British Medical Journal Publishing Group 06.04.2023 BMJ Publishing Group LTD
Subjects:	Adult Agonists Antidiabetics Bias Body mass index Body weight Cardiovascular disease Cerebral infarction Clinical practice guidelines Clinical trials Congestive heart failure Death Diabetes Diabetes mellitus (non-insulin dependent) Diabetes Mellitus, Type 2 - drug therapy Drugs Glucagon Glucagon-like peptide 1 Glucagon-Like Peptide-1 Receptor - therapeutic use Glucose Heart Failure - drug therapy Humans Insulin Kidney diseases Kidney Failure, Chronic Kidney transplants Meta-analysis Mineralocorticoid Receptor Antagonists - adverse effects Myocardial infarction Patients Quality of Life Randomized Controlled Trials as Topic Renal failure Sodium-glucose cotransporter Sodium-Glucose Transporter 2 Inhibitors - adverse effects Thiazolidinediones
ISSN:	1756-1833, 1756-1833
Online Access:	Get full text
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