Plasma neurofilament light chain levels suggest neuroaxonal stability following therapeutic remyelination in people with multiple sclerosis

BackgroundChronic demyelination is a major contributor to axonal vulnerability in multiple sclerosis (MS). Therefore, remyelination could provide a potent neuroprotective strategy. The ReBUILD trial was the first study showing evidence for successful remyelination following treatment with clemastine...

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Veröffentlicht in:	Journal of neurology, neurosurgery and psychiatry Jg. 93; H. 9; S. 972 - 977
Hauptverfasser:	Abdelhak, Ahmed, Cordano, Christian, Boscardin, W John, Caverzasi, Eduardo, Kuhle, Jens, Chan, Brandon, Gelfand, Jeffrey M, Yiu, Hao H, Oertel, Frederike C, Beaudry-Richard, Alexandra, Condor Montes, Shivany, Oksenberg, Jorge R, Lario Lago, Argentina, Boxer, Adam, Rojas-Martinez, Julio C, Elahi, Fanny M, Chan, Jonah R, Green, Ari J
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	England BMJ Publishing Group Ltd 01.09.2022 BMJ Publishing Group LTD
Schlagworte:	Biomarkers Body mass index Creatinine Magnetic resonance imaging Multiple sclerosis NEUROBIOLOGY Plasma Sample size Variance analysis United States > US San Francisco California California MULTIPLE SCLEROSIS NEUROBIOLOGY
ISSN:	0022-3050, 1468-330X, 1468-330X
Online-Zugang:	Volltext
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