Protocol for a randomised phase 3 trial evaluating the role of Finasteride in Active Surveillance for men with low and intermediate-risk prostate cancer: the FINESSE Study

BackgroundProstate cancer (PCa) is the most common male malignancy in the western world. Many men (40%) are diagnosed with localised low or intermediate-risk PCa, which is suitable for active surveillance (AS). AS affords careful monitoring to identify changes in otherwise non-life-threatening cance...

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Vydané v:	BMJ open Ročník 15; číslo 2; s. e096431
Hlavní autori:	Cumberbatch, Marcus, North, Bernard, Kealy, Roseann, Smith, Samuel, Hubbard, Rachel, Kennish, Steven, Bhattrai, Selina, Cross, William, Chahal, Rohit, Bryant, Richard, Lamb, Alastair D, Dooldeniya, Mohantha, Faulkner, Simon, Sasieni, Peter, Catto, James
Médium:	Journal Article
Jazyk:	English
Vydavateľské údaje:	England British Medical Journal Publishing Group 11.02.2025 BMJ Publishing Group LTD BMJ Publishing Group
Predmet:	5-alpha Reductase Inhibitors - therapeutic use Aged Antigens Biopsy Clinical Trials, Phase III as Topic Consent Disease Progression Finasteride - administration & dosage Finasteride - therapeutic use Humans Magnetic Resonance Imaging Male Medical ethics Medical research Middle Aged Mortality Patients Prospective Studies Prostate Prostate cancer Prostate-Specific Antigen - blood Prostatic Neoplasms Prostatic Neoplasms - drug therapy Prostatic Neoplasms - pathology Protocol Quality of Life Randomized Controlled Trials as Topic SURGERY Surveillance Urological tumours Urology Watchful Waiting - methods SURGERY Prostatic Neoplasms Urological tumours Prostate
ISSN:	2044-6055, 2044-6055
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