In Silico Designing and Screening of Antagonists against Cancer Drug Target XIAP

X-linked inhibitor of apoptosis (XIAP) is a member of inhibitor of apoptosis (IAP) family and involved in the suppression of apoptosis in cancer cells. This property makes it a therapeutic target for the cancer therapy. In the present study, we have developed QSAR models using chemical descriptors,...

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Veröffentlicht in:	Current cancer drug targets Jg. 15; H. 9; S. 836
Hauptverfasser:	Kumar, Rahul, Chauhan, Jagat Singh, Raghava, Gajendra Pal Singh
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	Netherlands 01.11.2015
Schlagworte:	Antineoplastic Agents - administration & dosage Antineoplastic Agents - chemistry Computer Simulation Drug Delivery Systems - methods Drug Design Drug Screening Assays, Antitumor - methods Humans Neoplasms - drug therapy Neoplasms - metabolism Quantitative Structure-Activity Relationship X-Linked Inhibitor of Apoptosis Protein - antagonists & inhibitors X-Linked Inhibitor of Apoptosis Protein - metabolism
ISSN:	1873-5576, 1873-5576
Online-Zugang:	Weitere Angaben
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