Application of Molecular Docking for the Development of Improved HIV-1 Reverse Transcriptase Inhibitors

Inhibition of the reverse transcriptase (RT) enzyme of the human immunodeficiency virus (HIV) by low molecular weight inhibitors is still an active area of research. Here, protein-ligand interactions and possible binding modes of novel compounds with the HIV-1 RT binding pocket (the wild-type as wel...

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Bibliographic Details

Published in:	Current computer-aided drug design Vol. 17; no. 4; p. 538
Main Authors:	Soltani, Arash, Hashemy, Seyed Isaac, Avval, Farnaz Zahedi, Rafatpanah, Houshang, Rezaee, Seyed Abdolrahim, Griffith, Renate, Mashkani, Baratali
Format:	Journal Article
Language:	English
Published:	United Arab Emirates 01.01.2021
Subjects:	Anti-HIV Agents - pharmacology HIV Infections - drug therapy HIV-1 Humans Molecular Docking Simulation Reverse Transcriptase Inhibitors - pharmacology gold interaction energy molecular docking HIV-1 RT reverse transcriptase NNRTIs
ISSN:	1875-6697, 1875-6697
Online Access:	Get more information
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