Diagnostic Approach and Treatment Regimens in Adult Patients Suffering from Antibody- mediated or Paraneoplastic Encephalitis

Identification of patients with antibody-mediated encephalitis poses a diagnostic challenge, and any delay in that aspect will increase the interval until the initiation of immunotherapy and may negatively affect the patient´s clinical outcome. Within this review, we focus on therapeutic strategies...

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Bibliographic Details
Published in:Current pharmaceutical design Vol. 28; no. 6; p. 454
Main Authors: Macher, Stefan, Bsteh, Gabriel, Berger, Thomas, Höftberger, Romana
Format: Journal Article
Language:English
Published: United Arab Emirates 01.01.2022
Subjects:
Adult
Autoantibodies
Encephalitis - diagnosis
Encephalitis - therapy
Humans
Immunotherapy
auto-antibodies
treatment
regimens
paraneoplastic encephalitis
immunotherapy
Antibody-mediated encephalitis
ISSN:1873-4286, 1873-4286
Online Access:Get more information
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Summary:Identification of patients with antibody-mediated encephalitis poses a diagnostic challenge, and any delay in that aspect will increase the interval until the initiation of immunotherapy and may negatively affect the patient´s clinical outcome. Within this review, we focus on therapeutic strategies in antibody-mediated encephalitis and propose how to proceed with patients who are suspected of having encephalitis of unknown origin. We further briefly outline differences in the treatment of paraneoplastic and antibody-mediated encephalitis according to its pathomechanisms.
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ISSN:1873-4286
1873-4286
DOI:10.2174/1381612828666220131093259