Improving outcome in SubaraChnoid HEMorrhage wIth nAdroparin (ISCHEMIA): a prospective randomised controlled trial protocol

IntroductionAneurysmal subarachnoid haemorrhage (aSAH) is a severe condition associated with significant morbidity and case fatality rate. Delayed cerebral ischaemia (DCI) is a major factor contributing to poor outcomes. For long, DCI was thought to be caused by vasospasm, induced by blood in the su...

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Bibliographic Details
Published in:	BMJ open Vol. 15; no. 8; p. e096555
Main Authors:	Denneman, Nadine, Doorschodt, Tom C, Coert, Bert A, van den Berg, René, Majoie, Charles B L M, Müller, Marcella C A, Middeldorp, Saskia, Coppens, Michiel, Kempeneers, Marinus A, Tjerkstra, Maud A, Labib, Homeyra, Bandral, Harssh Verdan, Baarse, Martine, Platek, Ewa E, Vandertop, W Peter, Verbaan, Dagmar, Post, René
Format:	Journal Article
Language:	English
Published:	England British Medical Journal Publishing Group 28.08.2025 BMJ Publishing Group LTD BMJ Publishing Group
Subjects:	Aneurysms Anticoagulants Anticoagulants - administration & dosage Anticoagulants - therapeutic use Anticoagulation Apoptosis Blood Brain damage Brain Ischemia - etiology Brain Ischemia - prevention & control Cerebral Hemorrhage Clinical outcomes Clinical Trials, Phase II as Topic Female Hemorrhage Hospital Mortality Humans Hypertension Informed consent Intervention Ischemia Male Medical imaging Mortality Nadroparin - administration & dosage Nadroparin - therapeutic use Neurology Neurosurgery Nitric oxide Patients Prospective Studies Randomized Controlled Trials as Topic Stroke Subarachnoid Hemorrhage - complications Subarachnoid Hemorrhage - drug therapy Subarachnoid Hemorrhage - mortality Treatment Outcome Stroke Anticoagulation Neurosurgery Cerebral Hemorrhage Mortality
ISSN:	2044-6055, 2044-6055
Online Access:	Get full text
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