Loss of Cyp11c1 causes delayed spermatogenesis due to the absence of 11-ketotestosterone

The impacts of androgens and glucocorticoids on spermatogenesis have intrigued scientists for decades. 11β-hydroxylase, encoded by cyp11c1, is the key enzyme involved in the synthesis of 11-ketotestosterone and cortisol, the major androgen and glucocorticoid in fish, respectively. In the present stu...

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Bibliographic Details

Published in:	Journal of endocrinology Vol. 244; no. 3; p. 487
Main Authors:	Zheng, Qiaoyuan, Xiao, Hesheng, Shi, Hongjuan, Wang, Tingru, Sun, Lina, Tao, Wenjing, Kocher, Thomas D, Li, Minghui, Wang, Deshou
Format:	Journal Article
Language:	English
Published:	England 01.03.2020
Subjects:	delayed spermatogenesis 11-ketotestosterone less semen CRISPR/Cas9 cyp11c1 undersized testis
ISSN:	1479-6805, 1479-6805
Online Access:	Get more information
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