From gene expression to serum proteins: biomarker discovery in ankylosing spondylitis

Objectives:Studying post-infliximab gene expression changes could provide insights into the pathogenesis of ankylosing spondylitis (AS).Methods:Gene expression changes were screened by microarray on peripheral blood RNA of 16 AS patients at baseline and 2 weeks post-infliximab, and selected results...

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Bibliographic Details
Published in:	Annals of the rheumatic diseases Vol. 69; no. 1; pp. 297 - 300
Main Authors:	Haroon, N, Tsui, F W L, O’Shea, F D, Chiu, B, Tsui, H W, Zhang, H, Marshall, K W, Inman, R D
Format:	Journal Article
Language:	English
Published:	England BMJ Publishing Group Ltd and European League Against Rheumatism 01.01.2010 Elsevier Limited
Subjects:	Adult Antibodies, Monoclonal - therapeutic use Antirheumatic Agents - therapeutic use Biomarkers - blood Blood Proteins - metabolism Blood Sedimentation C-Reactive Protein - metabolism Disease Female Gene expression Gene Expression Profiling - methods Humans Hypotheses Infliximab Laboratories Light Male Middle Aged Oligonucleotide Array Sequence Analysis - methods Patients Reverse Transcriptase Polymerase Chain Reaction - methods Severity of Illness Index Spondylitis, Ankylosing - blood Spondylitis, Ankylosing - drug therapy Tumor Necrosis Factor Ligand Superfamily Member 14 - blood Tumor necrosis factor-TNF Young Adult California
ISSN:	0003-4967, 1468-2060, 1468-2060
Online Access:	Get full text
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