PRDM16 controls smooth muscle cell fate in atherosclerosis

Vascular smooth muscle cells (SMCs) normally exist in a contractile state but can undergo fate switching to produce various cell phenotypes in response to pathologic stimuli . In atherosclerosis, these phenotypically modulated SMCs regulate plaque composition and influence the risk of major adverse...

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Veröffentlicht in:	bioRxiv
Hauptverfasser:	Tan, Josephine M E, Cheng, Lan, Calhoun, Ryan P, Weller, Angela H, Drareni, Karima, Fong, Skylar, Barbara, Eirlys, Lim, Hee-Woong, Xue, Chenyi, Winter, Hanna, Auguste, Gaëlle, Miller, Clint L, Reilly, Muredach P, Maegdefessel, Lars, Lutgens, Esther, Seale, Patrick
Format:	Journal Article Paper
Sprache:	Englisch
Veröffentlicht:	United States Cold Spring Harbor Laboratory Press 23.02.2025 Cold Spring Harbor Laboratory
Ausgabe:	1.1
Schlagworte:	Arteriosclerosis Atherosclerosis Cardiovascular diseases Cell fate Chromatin Fibrosis Histones Molecular Biology Muscle contraction Phenotypes Smooth muscle
ISSN:	2692-8205, 2692-8205
Online-Zugang:	Volltext
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