A microglia clonal inflammatory disorder in Alzheimer's Disease

Somatic genetic heterogeneity resulting from post-zygotic DNA mutations is widespread in human tissues and can cause diseases, however few studies have investigated its role in neurodegenerative processes such as Alzheimer's Disease (AD). Here we report the selective enrichment of microglia clo...

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Bibliographic Details

Published in:	bioRxiv
Main Authors:	Vicario, Rocio, Fragkogianni, Stamatina, Weber, Leslie, Lazarov, Tomi, Hu, Yang, Hayashi, Samantha Y, Craddock, Barbara P, Socci, Nicholas D, Alberdi, Araitz, Baako, Ann, Ay, Oyku, Ogishi, Masato, Lopez-Rodrigo, Estibaliz, Kappagantula, Rajya, Viale, Agnes, Iacobuzio-Donahue, Christine A, Zhou, Ting, Ransohoff, Richard M, Chesworth, Richard, Abdel-Wahab, Omar, Boisson, Bertrand, Elemento, Olivier, Casanova, Jean-Laurent, Miller, W Todd, Geissmann, Frederic
Format:	Journal Article Paper
Language:	English
Published:	United States Cold Spring Harbor Laboratory 03.08.2024
Edition:	1.2
Subjects:	Neuroscience
ISSN:	2692-8205, 2692-8205
Online Access:	Get full text
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