803 Triple checkpoint blockade, but not anti-PD1 alone, enhances the efficacy of engineered adoptive T cell therapy in advanced ovarian cancer

BackgroundOver 20,000 women are diagnosed with ovarian cancer annually, and more than half will die within 5 years. This rate has changed little in the last 30 years, highlighting the need for therapy innovation. T cells engineered to express a T cell receptor (TCR) targeting proteins uniquely overe...

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Veröffentlicht in:Journal for immunotherapy of cancer Jg. 11; H. Suppl 1; S. A902
Hauptverfasser: Anderson, Kristin G, Su, Yapeng, Burnett, Madison G, Bates, Breanna M, Suarez Gutierrez, Magdalia L, Ruskin, Susan L, Voillet, Valentin, Gottardo, Raphael, Greenberg, Philip D
Format: Journal Article
Sprache:Englisch
Veröffentlicht: London BMJ Publishing Group Ltd 01.11.2023
BMJ Publishing Group LTD
BMJ Publishing Group
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ISSN:2051-1426
Online-Zugang:Volltext
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