22 Humanized NOG-EXL mice exhibit improved overall survival and less severe myeloid cell activation relative to humanized NSG-SGM3 mice

BackgroundEngraftment efficiency of human immune cell lineages in super immunodeficient mice varies, and numerous strains have been developed to improve reconstitution of humanized immune system mice. NSG-SGM3 and NOG-EXL mice combine severe immunodeficiency with transgenic expression of human myelo...

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Veröffentlicht in:	Journal for immunotherapy of cancer Jg. 11; H. Suppl 1; S. A24
Hauptverfasser:	Willis, Elinor, Verrelle, Jillian, Banerjee, Esha, Assenmacher, Charles-Antoine, Tarrant, James C, Skuli, Nicolas, Jacobson, Moriah L, Binder, Zev, Radaelli, Enrico
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	London BMJ Publishing Group Ltd 01.11.2023 BMJ Publishing Group LTD BMJ Publishing Group
Schlagworte:	Hyperplasia Immunotherapy Regular and Young Investigator Award Abstracts Stem cells
ISSN:	2051-1426
Online-Zugang:	Volltext
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