549 Characterizing double positive T cells in the tumor microenvironment: a tale of promiscuous cell fates

BackgroundCD4 and CD8 T cells are genetically and functionally distinct cell subsets of the adaptive immune system that play pivotal roles in immune surveillance and disease control. During development in the thymus, transcription factors ThPOK and Runx3 regulate the differentiation and maturation o...

Full description

Bibliographic Details

Published in:	Journal for immunotherapy of cancer Vol. 8; no. Suppl 3; pp. A333 - A334
Main Authors:	Schad, Sara, Chow, Andrew, Pan, Heng, Mangarin, Levi, Zappasodi, Roberta, Gigoux, Mathieu, Redmond, David, Hirschhorn-Cymerman, Daniel, Budhu, Sadna, Zhong, Hong, Yang, Xia, Elemento, Olivier, Wolchok, Jedd, Merghoub, Taha
Format:	Journal Article
Language:	English
Published:	London BMJ Publishing Group LTD 01.11.2020 BMJ Publishing Group
Subjects:	Antigens Antiviral drugs Cytotoxicity Immunotherapy Kidney cancer Lymphocytes Melanoma Tumors Urological cancer
ISSN:	2051-1426
Online Access:	Get full text
Tags:	Add Tag No Tags, Be the first to tag this record!