549 Characterizing double positive T cells in the tumor microenvironment: a tale of promiscuous cell fates

BackgroundCD4 and CD8 T cells are genetically and functionally distinct cell subsets of the adaptive immune system that play pivotal roles in immune surveillance and disease control. During development in the thymus, transcription factors ThPOK and Runx3 regulate the differentiation and maturation o...

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Veröffentlicht in:	Journal for immunotherapy of cancer Jg. 8; H. Suppl 3; S. A333 - A334
Hauptverfasser:	Schad, Sara, Chow, Andrew, Pan, Heng, Mangarin, Levi, Zappasodi, Roberta, Gigoux, Mathieu, Redmond, David, Hirschhorn-Cymerman, Daniel, Budhu, Sadna, Zhong, Hong, Yang, Xia, Elemento, Olivier, Wolchok, Jedd, Merghoub, Taha
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	London BMJ Publishing Group LTD 01.11.2020 BMJ Publishing Group
Schlagworte:	Antigens Antiviral drugs Cytotoxicity Immunotherapy Kidney cancer Lymphocytes Melanoma Tumors Urological cancer
ISSN:	2051-1426
Online-Zugang:	Volltext
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