Evolutionary Dynamics of Non-Coding Regions in Pancreatic Ductal Adenocarcinoma

Abstract While the non-coding genome appears to play a role, the dynamic nature of noncoding alterations with respect to clonal progression of solid tumors remains unexplored. To address this gap in knowledge we performed multiregional whole genome sequencing and clonal analysis to elucidate the evo...

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Bibliographic Details

Published in:	bioRxiv
Main Authors:	Hayashi, Akimasa, Yu-Jui, Ho, Makohon-Moore, Alvin P, Zucker, Amanda, Hong, Jungeui, Reiter, Johannes G, Huang, Jinlong, Zhang, Lance, Attiyeh, Marc A, Baez, Priscilla, Kappagantula, Rajya, Melchor, Jerry P, Eileen M O’reilly, Socci, Nicholas D, Oki, Shinya, Lowe, Scott W, Iacobuzio-Donahue, Christine A
Format:	Paper
Language:	English Japanese
Published:	Cold Spring Harbor Cold Spring Harbor Laboratory Press 12.09.2020 Cold Spring Harbor Laboratory
Edition:	1.1
Subjects:	Adenocarcinoma Cancer Biology Deoxyribonucleic acid DNA Genomes Pancreatic cancer Solid tumors Whole genome sequencing
ISSN:	2692-8205, 2692-8205
Online Access:	Get full text
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