Metabolically Primed Multipotent Hematopoietic Progenitors Fuel Innate Immunity

Following infection, hematopoietic stem and progenitor cells (HSPCs) support immunity by increasing the rate of innate immune cell production but the metabolic cues that guide this process are unknown. To address this question, we developed MetaFate, a method to trace the metabolic expression state...

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Bibliographic Details

Published in:	bioRxiv
Main Authors:	Cosgrove, Jason, Lyne, Anne-Marie, Rodriguez, Ildefonso, Cabeli, Vincent, Conrad, Cecile, Tenreira-Bento, Sabrina, Tubeuf, Emilie, Russo, Erica, Tabarin, Fanny, Belloucif, Yannis, Maleki-Toyserkani, Shayda, Reed, Sophie, Monaco, Federica, Ager, Ann, Lobry, Camille, Bousso, Philippe, Fernández-Marcos, Pablo Jose, Isambert, Herve, Argüello, Rafael J., Perié, Leïla
Format:	Paper
Language:	English
Published:	Cold Spring Harbor Laboratory 24.01.2023
Edition:	1.1
Subjects:	Immunology
ISSN:	2692-8205
Online Access:	Get full text
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