045  Effect of siponimod on cortical grey matter and thalamic volume in secondary progressive multiple sclerosis

BackgroundGrey matter (GM) loss is associated with cognitive decline and physical disability in multiple sclerosis (MS). In Phase 3 EXPAND study, siponimod significantly reduced disability progression, cognitive decline and whole brain volume loss in patients with secondary progressive MS (SPMS).Met...

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Bibliographic Details

Published in:	Journal of neurology, neurosurgery and psychiatry Vol. 93; no. 6; p. A27
Main Authors:	Arnold, Douglas L, Fox, Robert J, Bar-Or, Amit, Cree, Bruce AC, Giovannoni, Gavin, Gold, Ralf, Vermersch, Pat- rick, Meier, Daniela Piani, Arnould, Sophie, Kappos, Ludwig
Format:	Journal Article
Language:	English
Published:	London BMJ Publishing Group Ltd 01.06.2022 BMJ Publishing Group LTD
Subjects:	ABN Abstracts 2020 Magnetic resonance imaging Multiple sclerosis
ISSN:	0022-3050, 1468-330X
Online Access:	Get full text
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