Learning Optimal White Matter Tract Representations from Tractography using a Deep Generative Model for Population Analyses

Whole brain tractography is commonly used to study the brain's white matter fiber pathways, but the large number of streamlines generated - up to one million per brain - can be challenging for large-scale population studies. We propose a robust dimensionality reduction framework for tractograph...

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Bibliographic Details

Published in:	bioRxiv
Main Authors:	Feng, Yixue, Bramsh Qamar Chandio, Chattopadhyay, Tamoghna, Thomopoulos, Sophia I, Owens-Walton, Conor, Jahanshad, Neda, Garyfallidis, Eleftherios, Thompson, Paul M
Format:	Paper
Language:	English
Published:	Cold Spring Harbor Cold Spring Harbor Laboratory Press 02.08.2022 Cold Spring Harbor Laboratory
Edition:	1.1
Subjects:	Alzheimer's disease Embedding Neurodegenerative diseases Neuroscience Population studies Statistical analysis Substantia alba diffusion MRI tractography anomaly detection Alzheimer’s disease variational autoencoder
ISSN:	2692-8205, 2692-8205
Online Access:	Get full text
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