Accelerated single cell seeding in relapsed multiple myeloma

The malignant progression of multiple myeloma is characterized by the seeding of cancer cells in different anatomic sites followed by their clonal expansion. It has been demonstrated that this spatial evolution at varying anatomic sites is characterized by genomic heterogeneity. However, it is uncle...

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Veröffentlicht in:	bioRxiv
Hauptverfasser:	Landau, Heather J, Yellapantula, Venkata, Diamond, Benjamin J, Rustad, Even H, Maclachlan, Kylee, Gunes Gundem, Medina-Martinez, Juan, Arango Ossa, Juan E, Levine, Max, Zhou, Yangyu, Rajya, Kappagantula L, Baez, Priscilla, Attiyeh, Marc, Makohon-Moore, Alvin, Zhang, Lance, Boyle, Eileen E, Ashby, Cody, Blaney, Patrick, Patel, Minal, Zhang, Yanming, Dogan, Ahmet, Chung, David, Giralt, Sergio, Lahoud, Oscar B, Peled, Jonathan, Scordo, Michael, Shah, Gunjan, Hassoun, Hani, Korde, Neha S, Lesokhin, Alexander M, Lu, Sydney, Sham Mailankody, Shah, Urvi A, Smith, Eric, Hultcrantz, Malin L, Ulaner, Gary, Frits Van Rhee, Morgan, Gareth, Landgren, Ola, Papaemmanuil, Elli, Iacobuzio-Donahue, Christine A, Francesco, Maura
Format:	Paper
Sprache:	Englisch
Veröffentlicht:	Cold Spring Harbor Cold Spring Harbor Laboratory Press 26.02.2020 Cold Spring Harbor Laboratory
Ausgabe:	1.1
Schlagworte:	Autografts Autopsy Cancer Cancer Biology Cancer therapies Chemotherapy Copy number Evolution Genomes Melphalan Multiple myeloma Mutation Patients Platinum Whole genome sequencing Mutational Signatures Chemotherapy Warm autopsy Seeding Multiple Myeloma
ISSN:	2692-8205, 2692-8205
Online-Zugang:	Volltext
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