Accelerated single cell seeding in relapsed multiple myeloma

The malignant progression of multiple myeloma is characterized by the seeding of cancer cells in different anatomic sites followed by their clonal expansion. It has been demonstrated that this spatial evolution at varying anatomic sites is characterized by genomic heterogeneity. However, it is uncle...

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Bibliographic Details
Published in:	bioRxiv
Main Authors:	Landau, Heather J, Yellapantula, Venkata, Diamond, Benjamin J, Rustad, Even H, Maclachlan, Kylee, Gunes Gundem, Medina-Martinez, Juan, Arango Ossa, Juan E, Levine, Max, Zhou, Yangyu, Rajya, Kappagantula L, Baez, Priscilla, Attiyeh, Marc, Makohon-Moore, Alvin, Zhang, Lance, Boyle, Eileen E, Ashby, Cody, Blaney, Patrick, Patel, Minal, Zhang, Yanming, Dogan, Ahmet, Chung, David, Giralt, Sergio, Lahoud, Oscar B, Peled, Jonathan, Scordo, Michael, Shah, Gunjan, Hassoun, Hani, Korde, Neha S, Lesokhin, Alexander M, Lu, Sydney, Sham Mailankody, Shah, Urvi A, Smith, Eric, Hultcrantz, Malin L, Ulaner, Gary, Frits Van Rhee, Morgan, Gareth, Landgren, Ola, Papaemmanuil, Elli, Iacobuzio-Donahue, Christine A, Francesco, Maura
Format:	Paper
Language:	English
Published:	Cold Spring Harbor Cold Spring Harbor Laboratory Press 26.02.2020 Cold Spring Harbor Laboratory
Edition:	1.1
Subjects:	Autografts Autopsy Cancer Cancer Biology Cancer therapies Chemotherapy Copy number Evolution Genomes Melphalan Multiple myeloma Mutation Patients Platinum Whole genome sequencing Mutational Signatures Chemotherapy Warm autopsy Seeding Multiple Myeloma
ISSN:	2692-8205, 2692-8205
Online Access:	Get full text
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