Transient Commensal Clonal Interactions Can Drive Tumor Metastasis

To interrogate functional heterogeneity and crosstalk between tumor cells, we generated clonal populations from a patient-derived ovarian clear cell carcinoma model which forms malignant ascites and solid peritoneal tumors upon intraperitoneal transplantation in mice. The clonal populations were eng...

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Bibliographic Details

Published in:	bioRxiv
Main Authors:	Suha Naffar-Abu Amara, Kuiken, Hendrik J, Selfors, Laura M, Butler, Timothy, Leung, Marco L, Leung, Cheuk T, Kuhn, Elaine P, Kolarova, Teodora R, Hage, Carina, Ganesh, Kripa, Foster, Rosemary, Rueda, Bo R, Aktipis, Athena, Spellman, Paul T, Ince, Tan, Navin, Nicholas, Mills, Gordon B, Bronson, Rodrick T, Brugge, Joan S S
Format:	Paper
Language:	English
Published:	Cold Spring Harbor Cold Spring Harbor Laboratory Press 16.01.2020 Cold Spring Harbor Laboratory
Edition:	1.1
Subjects:	Amphiregulin Ascites Cancer Biology ErbB-2 protein Metastases Metastasis Peritoneum Transplantation Tumor cells Tumors
ISSN:	2692-8205, 2692-8205
Online Access:	Get full text
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