The Alzheimer conundrum entanglements of dementia and aging

Due to rapidly aging populations, the number of people worldwide experiencing dementia is increasing, and the projections are grim. Despite billions of dollars invested in medical research, no effective treatment has been discovered for Alzheimer's disease, the most common form of dementia. The...

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Hlavní autor:	Lock, Margaret
Médium:	E-kniha Kniha
Jazyk:	angličtina
Vydáno:	Princeton, N.J Princeton University Press 2013
Vydání:	1
Témata:	Age factors Age of onset Aging Allele Alzheimer's Association Alzheimer's disease Alzheimer's disease > Age factors Amnesia Amyloid Amyloid beta Anthropology Apolipoprotein E Biomarker Brain Brain > Aging > Molecular aspects Cardiovascular disease Caregiver Cell death Cerebrospinal fluid Clinical trial Clinician Dementia Diagnosis Disease Drug development Early-onset Alzheimer's disease Epidemic Epidemiology Family history (medicine) Family support Finding Follow-up Funding General practitioner Genetic counseling Genetic testing Geneticist Genome-wide association study Genotype Genotyping HEALTH & FITNESS / Diseases / Alzheimer's & Dementia Health Sciences History of Science & Technology Human subject research Inflammation MEDICAL / General Medical diagnosis Mental disorder Mental health Mild cognitive impairment Model organism Molecular aspects Molecular biology National Institute on Aging Neurodegeneration Neurofibrillary tangle Neuroimaging Neurology Neuropathology Old age Older people Older people > Mental health Oxidative stress Pathology Pharmaceutical drug Pharmaceutical industry Physician Positron emission tomography Prevalence Principal investigator Processing (Chinese materia medica) Psychiatrist Psychiatry Public health Research assistant Risk factor SCIENCE / History Scientist SOCIAL SCIENCE SOCIAL SCIENCE / Anthropology / General Specialty (medicine) Symptom Syndrome Technology Toxin Uncertainty Vascular dementia Prevalence Disease Funding Research assistant Caregiver Cardiovascular disease Cerebrospinal fluid Drug development Principal investigator Human subject research Epidemiology Old age National Institute on Aging Follow-up Family history (medicine) Family support Technology Neurodegeneration Diagnosis Pharmaceutical industry Alzheimer's disease Alzheimer's Association Public health Epidemic Vascular dementia Scientist Genotype Processing (Chinese materia medica) Neurofibrillary tangle Model organism Pathology Neurology Genotyping Risk factor Finding Dementia Neuroimaging Oxidative stress Biomarker Uncertainty Neuropathology Early-onset Alzheimer's disease Pharmaceutical drug Mild cognitive impairment Medical diagnosis Psychiatrist Clinician Amyloid beta Age of onset Genome-wide association study Apolipoprotein E Clinical trial Amyloid Amnesia Symptom Specialty (medicine) General practitioner Physician Inflammation Geneticist Syndrome Toxin Allele Genetic counseling Cell death Mental disorder Genetic testing Molecular biology Psychiatry Positron emission tomography
ISBN:	9780691149783, 069114978X, 1400848466, 9781400848461, 9780691168470, 0691168474
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Popis
Shrnutí:	Due to rapidly aging populations, the number of people worldwide experiencing dementia is increasing, and the projections are grim. Despite billions of dollars invested in medical research, no effective treatment has been discovered for Alzheimer's disease, the most common form of dementia. The Alzheimer Conundrum exposes the predicaments embedded in current efforts to slow down or halt Alzheimer’s disease through early detection of pre-symptomatic biological changes in healthy individuals. Based on a meticulous account of the history of Alzheimer’s disease and extensive in-depth interviews, Margaret Lock highlights the limitations and the dissent associated with biomarker detection. Lock argues that basic research must continue, but should be complemented by a public health approach to prevention that is economically feasible, more humane, and much more effective globally than one exclusively focused on an increasingly harried search for a cure. Margaret Lock is the Marjorie Bronfman Professor Emerita in the Department of Social Studies of Medicine and the Department of Anthropology at McGill University.
Bibliografie:	"First paperback printing, 2016"--T.p. verso Originally published: 2013
ISBN:	9780691149783 069114978X 1400848466 9781400848461 9780691168470 0691168474
DOI:	10.1515/9781400848461