Automated Nanoflow Two-Dimensional Reversed-Phase Liquid Chromatography System Enables In-Depth Proteome and Phosphoproteome Profiling of Nanoscale Samples

Two-dimensional reversed-phase capillary liquid chromatography (2D RPLC) separations have enabled comprehensive proteome profiling of biological systems. However, milligram sample quantities of proteins are typically required due to significant losses during offline fractionation. Such a large sampl...

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Bibliographic Details
Published in:Analytical chemistry (Washington) Vol. 91; no. 15; p. 9707
Main Authors: Dou, Maowei, Tsai, Chia-Feng, Piehowski, Paul D, Wang, Yang, Fillmore, Thomas L, Zhao, Rui, Moore, Ronald J, Zhang, Pengfei, Qian, Wei-Jun, Smith, Richard D, Liu, Tao, Kelly, Ryan T, Shi, Tujin, Zhu, Ying
Format: Journal Article
Language:English
Published: United States 06.08.2019
ISSN:1520-6882, 1520-6882
Online Access:Get more information
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