Epidemiology of Neuromyelitis Optica in the World: A Systematic Review and Meta-Analysis

Background. Neuromyelitis optica (Devic’s disease) is a severe autoimmune inflammatory disorder of the central nervous system. Epidemiological aspects of NMO have not been systemically reviewed. In this study we systematically reviewed and assessed the quality of studies reporting the incidence and/...

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Published in:Multiple Sclerosis International Vol. 2015; no. 2015; pp. 14 - 21
Main Authors: Taherioun, Maryam, Khalili, Behrang, Nasr, Zahra, Etemadifar, Masoud, Vosoughi, Reza
Format: Journal Article
Language:English
Published: Cairo, Egypt Hindawi Limiteds 01.01.2015
Hindawi Publishing Corporation
John Wiley & Sons, Inc
Subjects:
Data collection
Diagnosis
Epidemiology
Estimates
Meta-analysis
Multiple sclerosis
Neuromyelitis optica
Prevalence studies (Epidemiology)
Quality
Review
Spinal cord
Studies
Systematic review
Iran
Canada
Denmark
Cuba
ISSN:2090-2654, 2090-2662
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Abstract Background. Neuromyelitis optica (Devic’s disease) is a severe autoimmune inflammatory disorder of the central nervous system. Epidemiological aspects of NMO have not been systemically reviewed. In this study we systematically reviewed and assessed the quality of studies reporting the incidence and/or prevalence of NMO across the world. Methods. A comprehensive literature search using MEDLINE, EMBASE, and Web of Science for the terms “Neuromyelitis optica,” “devic disease,” “incidence,” “prevalence,” and “epidemiology” was conducted on January 31, 2015. Study quality was assessed using an assessment tool based on recognized guidelines and designed specifically for this study. Results. A total of 216 studies were initially identified, with only 9 meeting the inclusion criteria. High level of heterogeneity amongst studies precluded a firm conclusion. Incidence data were found in four studies and ranged from 0.053 per 100,000 per year in Cuba to 0.4 in Southern Denmark. Prevalence was reported in all studies and ranged from 0.51 per 100,000 in Cuba to 4.4 in Southern Denmark. Conclusion. This review reveals the gaps that still exist in the epidemiological knowledge of NMO in the world. Published studies have different qualities and methodology precluding a robust conclusion. Future researches focusing on epidemiological features of NMO in different nations and different ethnic groups are needed.
AbstractList Background. Neuromyelitis optica (Devic’s disease) is a severe autoimmune inflammatory disorder of the central nervous system. Epidemiological aspects of NMO have not been systemically reviewed. In this study we systematically reviewed and assessed the quality of studies reporting the incidence and/or prevalence of NMO across the world. Methods. A comprehensive literature search using MEDLINE, EMBASE, and Web of Science for the terms “Neuromyelitis optica,” “devic disease,” “incidence,” “prevalence,” and “epidemiology” was conducted on January 31, 2015. Study quality was assessed using an assessment tool based on recognized guidelines and designed specifically for this study. Results. A total of 216 studies were initially identified, with only 9 meeting the inclusion criteria. High level of heterogeneity amongst studies precluded a firm conclusion. Incidence data were found in four studies and ranged from 0.053 per 100,000 per year in Cuba to 0.4 in Southern Denmark. Prevalence was reported in all studies and ranged from 0.51 per 100,000 in Cuba to 4.4 in Southern Denmark. Conclusion. This review reveals the gaps that still exist in the epidemiological knowledge of NMO in the world. Published studies have different qualities and methodology precluding a robust conclusion. Future researches focusing on epidemiological features of NMO in different nations and different ethnic groups are needed.
Background. Neuromyelitis optica (Devic's disease) is a severe autoimmune inflammatory disorder of the central nervous system. Epidemiological aspects of NMO have not been systemically reviewed. In this study we systematically reviewed and assessed the quality of studies reporting the incidence and/or prevalence of NMO across the world. Methods. A comprehensive literature search using MEDLINE, EMBASE, and Web of Science for the terms "Neuromyelitis optica," "devic disease," "incidence," "prevalence," and "epidemiology" was conducted on January 31, 2015. Study quality was assessed using an assessment tool based on recognized guidelines and designed specifically for this study. Results. A total of 216 studies were initially identified, with only 9 meeting the inclusion criteria. High level of heterogeneity amongst studies precluded a firm conclusion. Incidence data were found in four studies and ranged from 0.053 per 100,000 per year in Cuba to 0.4 in Southern Denmark. Prevalence was reported in all studies and ranged from 0.51 per 100,000 in Cuba to 4.4 in Southern Denmark. Conclusion. This review reveals the gaps that still exist in the epidemiological knowledge of NMO in the world. Published studies have different qualities and methodology precluding a robust conclusion. Future researches focusing on epidemiological features of NMO in different nations and different ethnic groups are needed.
Audience Academic
Author Taherioun, Maryam
Khalili, Behrang
Etemadifar, Masoud
Nasr, Zahra
Vosoughi, Reza
AuthorAffiliation 1 Isfahan Research Committee of Multiple Sclerosis, Behesht Building Bozorgmehr Avenue, Isfahan 81588-44799, Iran
2 Medical Students' Research Center, Isfahan University of Medical Sciences, Isfahan, Iran
3 Health Sciences Centre, University of Manitoba, Winnipeg, MB, Canada R3A 1R9
AuthorAffiliation_xml – name: 2 Medical Students' Research Center, Isfahan University of Medical Sciences, Isfahan, Iran
– name: 3 Health Sciences Centre, University of Manitoba, Winnipeg, MB, Canada R3A 1R9
– name: 1 Isfahan Research Committee of Multiple Sclerosis, Behesht Building Bozorgmehr Avenue, Isfahan 81588-44799, Iran
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  fullname: Khalili, Behrang
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  fullname: Nasr, Zahra
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  fullname: Etemadifar, Masoud
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  fullname: Vosoughi, Reza
BackLink https://www.ncbi.nlm.nih.gov/pubmed/25973275$$D View this record in MEDLINE/PubMed
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Cites_doi 10.1016/s0140-6736(04)17551-x
10.1136/jnnp.2007.131177
10.1007/s00415-008-0781-2
10.1212/01.wnl.0000216139.44259.74
10.1177/1352458514521503
10.1016/j.neurol.2009.02.012
10.1212/WNL.56.4.507
10.1212/wnl.53.5.1107
10.1007/s00415-009-0009-0
10.1016/j.jneuroim.2010.10.012
10.1212/wnl.0b013e318248dec1
10.1016/j.jns.2011.01.002
10.1177/1352458507084595
10.1212/wnl.0b013e3182190f74
10.1111/j.1468-1331.2011.03529.x
10.1016/j.jns.2012.08.032
10.1136/ebmh.1.2.37
10.1177/1352458509104595
10.1007/s00415-013-6926-y
10.1177/1352458514537699
10.1212/WNL.53.5.1107
10.1002/ana.410400405
10.1016/s1474-4422(03)00308-9
10.1093/brain/awm027
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References (5) 1999; 53
(14) 2012; 323
(23) 1996; 40
(6) 1998; 1
(8) 2012; 19
(13) 2014; 20
(1) 2006; 66
(26) 2002; 8
(15) 2008; 255
(25) 2001; 56
http://www.msif.org
(3) 2004; 364
(10) 2013; 260
(18) 1999; 53
(19) 2008; 14
(17) 2006; 66
(21) 2009; 15
(27) 2008; 79
(7) 2011; 76
(24) 2007; 130
(22) 2003; 2
(9) 2014; 20
(12) 2009; 256
(4) 2011; 231
(11) 2009; 165
(2) 2011; 303
(20) 2012; 78
22
23
25
26
27
10
11
12
13
14
15
17
18
19
1
2
3
4
5
6
7
8
9
(24) 2002; 8
20
21
8871575 - Ann Neurol. 1996 Oct;40(4):569-74
24493471 - Mult Scler. 2014 Oct;20(12):1651-3
12849268 - Lancet Neurol. 2003 Feb;2(2):117-27
19224310 - J Neurol. 2009 Jan;256(1):35-44
17439988 - Brain. 2007 May;130(Pt 5):1206-23
23689970 - J Neurol. 2013 Aug;260(8):2134-7
19465451 - Mult Scler. 2009 Jul;15(7):834-47
11222796 - Neurology. 2001 Feb 27;56(4):507-14
21967235 - Eur J Neurol. 2012 Apr;19(4):655-9
15589308 - Lancet. 2004 Dec 11-17;364(9451):2106-12
24948686 - Mult Scler. 2014 Dec;20(14):1920-2
21300379 - J Neurol Sci. 2011 Apr 15;303(1-2):13-21
22302543 - Neurology. 2012 Feb 28;78(9):665-71; discussion 669
16717206 - Neurology. 2006 May 23;66(10 ):1485-9
21067820 - J Neuroimmunol. 2011 Feb;231(1-2):100-4
10496275 - Neurology. 1999 Sep 22;53(5):1107-14
11937660 - Hong Kong Med J. 2002 Apr;8(2):77-80
21536639 - Neurology. 2011 May 3;76(18):1589-95
22995683 - J Neurol Sci. 2012 Dec 15;323(1-2):117-22
19406445 - Rev Neurol (Paris). 2009 Aug-Sep;165(8-9):676-83
18356258 - J Neurol Neurosurg Psychiatry. 2008 Sep;79(9):1022-6
18208892 - Mult Scler. 2008 May;14(4):440-5
18283393 - J Neurol. 2008 May;255(5):710-5
References_xml – volume: 14
  start-page: 440
  issue: 4
  year: 2008
  end-page: 445
  ident: 19
  article-title: NMO-IgG and Devic's neuromyelitis optica: a French experience
– volume: 303
  start-page: 13
  issue: 1-2
  year: 2011
  end-page: 21
  ident: 2
  article-title: Neuromyelitis optica: an update
– volume: 66
  start-page: 1485
  issue: 10
  year: 2006
  end-page: 1489
  ident: 1
  article-title: Revised diagnostic criteria for neuromyelitis optica
– volume: 260
  start-page: 2134
  issue: 8
  year: 2013
  end-page: 2137
  ident: 10
  article-title: The epidemiology of neuromyelitis optica amongst adults in the Merseyside county of United Kingdom
– volume: 2
  start-page: 117
  issue: 2
  year: 2003
  end-page: 127
  ident: 22
  article-title: Multiple sclerosis in the Japanese population
– volume: 66
  start-page: 1485
  issue: 10
  year: 2006
  end-page: 1489
  ident: 17
  article-title: Revised diagnostic criteria for neuromyelitisoptica
– volume: 8
  start-page: 77
  issue: 2
  year: 2002
  end-page: 80
  ident: 26
  article-title: Epidemiological study of multiple sclerosis in Hong Kong Chinese: questionnaire survey
– volume: 78
  start-page: 665
  issue: 9
  year: 2012
  end-page: 671
  ident: 20
  article-title: Serologic diagnosis of NMO: a multicenter comparison of aquaporin-4-IgG assays
– volume: 76
  start-page: 1589
  issue: 18
  year: 2011
  end-page: 1595
  ident: 7
  article-title: A population-based study of neuromyelitis optica in Caucasians
– volume: 1
  start-page: 37
  issue: 2
  year: 1998
  end-page: 39
  ident: 6
  article-title: Guidelines for evaluating prevalence studies
– volume: 56
  start-page: 507
  issue: 4
  year: 2001
  end-page: 514
  ident: 25
  article-title: MS and neuromyelitis optica in Martinique (French West Indies)
– reference: http://www.msif.org
– volume: 20
  start-page: 1920
  issue: 14
  year: 2014
  end-page: 1922
  ident: 9
  article-title: An epidemiological study of neuromyelitis optica in Isfahan
– volume: 255
  start-page: 710
  issue: 5
  year: 2008
  end-page: 715
  ident: 15
  article-title: Characteristics of Devic's disease (neuromyelitis optica) in Mexico
– volume: 15
  start-page: 834
  issue: 7
  year: 2009
  end-page: 847
  ident: 21
  article-title: Aquaporin-4 autoimmune syndrome and anti-aquaporin-4 antibody-negative opticospinal multiple sclerosis in Japanese
– volume: 79
  start-page: 1022
  issue: 9
  year: 2008
  end-page: 1026
  ident: 27
  article-title: Characterisation of the spectrum of demyelinating disease in Western Australia
– volume: 130
  start-page: 1206
  issue: 5
  year: 2007
  end-page: 1223
  ident: 24
  article-title: Heterogeneity of aquaporin-4 autoimmunity and spinal cord lesions in multiple sclerosis in Japanese
– volume: 20
  start-page: 1651
  issue: 12
  year: 2014
  end-page: 1653
  ident: 13
  article-title: Prevalence and patterns of demyelinating central nervous system disorders in urban Mangalore, South India
– volume: 323
  start-page: 117
  issue: 1-2
  year: 2012
  end-page: 122
  ident: 14
  article-title: Increased prevalence, incidence, and female predominance of multiple sclerosis in northern Japan
– volume: 231
  start-page: 100
  issue: 1-2
  year: 2011
  end-page: 104
  ident: 4
  article-title: Neuromyelitis optica: concepts in evolution
– volume: 165
  start-page: 676
  issue: 8-9
  year: 2009
  end-page: 683
  ident: 11
  article-title: Descriptive epidemiology of neuromyelitis optica in the Caribbean basin
– volume: 19
  start-page: 655
  issue: 4
  year: 2012
  end-page: 659
  ident: 8
  article-title: The prevalence of neuromyelitis optica in South East Wales
– volume: 40
  start-page: 569
  issue: 4
  year: 1996
  end-page: 574
  ident: 23
  article-title: Western versus Asian types of multiple sclerosis: immunogenetically and clinically distinct disorders
– volume: 364
  start-page: 2106
  issue: 9451
  year: 2004
  end-page: 2112
  ident: 3
  article-title: A serum autoantibody marker of neuromyelitis optica: distinction from multiple sclerosis
– volume: 53
  start-page: 1107
  issue: 5
  year: 1999
  end-page: 1114
  ident: 5
  article-title: The clinical course of neuromyelitis optica (Devic's syndrome)
– volume: 256
  start-page: 35
  issue: 1
  year: 2009
  end-page: 44
  ident: 12
  article-title: An epidemiological study of neuromyelitis optica in Cuba
– volume: 53
  start-page: 1107
  issue: 5
  year: 1999
  end-page: 1114
  ident: 18
  article-title: The clinical course of neuromyelitis optica (Devic's syndrome)
– ident: 3
  doi: 10.1016/s0140-6736(04)17551-x
– ident: 25
  doi: 10.1136/jnnp.2007.131177
– ident: 14
  doi: 10.1007/s00415-008-0781-2
– ident: 1
  doi: 10.1212/01.wnl.0000216139.44259.74
– ident: 13
  doi: 10.1177/1352458514521503
– ident: 11
  doi: 10.1016/j.neurol.2009.02.012
– ident: 23
  doi: 10.1212/WNL.56.4.507
– volume: 8
  start-page: 77
  issue: 2
  year: 2002
  ident: 24
  publication-title: Hong Kong Medical Journal
– ident: 27
  doi: 10.1212/wnl.53.5.1107
– ident: 12
  doi: 10.1007/s00415-009-0009-0
– ident: 4
  doi: 10.1016/j.jneuroim.2010.10.012
– ident: 18
  doi: 10.1212/wnl.0b013e318248dec1
– ident: 2
  doi: 10.1016/j.jns.2011.01.002
– ident: 26
  doi: 10.1212/01.wnl.0000216139.44259.74
– ident: 17
  doi: 10.1177/1352458507084595
– ident: 7
  doi: 10.1212/wnl.0b013e3182190f74
– ident: 8
  doi: 10.1111/j.1468-1331.2011.03529.x
– ident: 15
  doi: 10.1016/j.jns.2012.08.032
– ident: 6
  doi: 10.1136/ebmh.1.2.37
– ident: 19
  doi: 10.1177/1352458509104595
– ident: 10
  doi: 10.1007/s00415-013-6926-y
– ident: 9
  doi: 10.1177/1352458514537699
– ident: 5
  doi: 10.1212/WNL.53.5.1107
– ident: 21
  doi: 10.1002/ana.410400405
– ident: 20
  doi: 10.1016/s1474-4422(03)00308-9
– ident: 22
  doi: 10.1093/brain/awm027
– reference: 18208892 - Mult Scler. 2008 May;14(4):440-5
– reference: 22302543 - Neurology. 2012 Feb 28;78(9):665-71; discussion 669
– reference: 24493471 - Mult Scler. 2014 Oct;20(12):1651-3
– reference: 12849268 - Lancet Neurol. 2003 Feb;2(2):117-27
– reference: 21067820 - J Neuroimmunol. 2011 Feb;231(1-2):100-4
– reference: 11222796 - Neurology. 2001 Feb 27;56(4):507-14
– reference: 10496275 - Neurology. 1999 Sep 22;53(5):1107-14
– reference: 21536639 - Neurology. 2011 May 3;76(18):1589-95
– reference: 11937660 - Hong Kong Med J. 2002 Apr;8(2):77-80
– reference: 23689970 - J Neurol. 2013 Aug;260(8):2134-7
– reference: 22995683 - J Neurol Sci. 2012 Dec 15;323(1-2):117-22
– reference: 18356258 - J Neurol Neurosurg Psychiatry. 2008 Sep;79(9):1022-6
– reference: 24948686 - Mult Scler. 2014 Dec;20(14):1920-2
– reference: 19224310 - J Neurol. 2009 Jan;256(1):35-44
– reference: 21300379 - J Neurol Sci. 2011 Apr 15;303(1-2):13-21
– reference: 8871575 - Ann Neurol. 1996 Oct;40(4):569-74
– reference: 19406445 - Rev Neurol (Paris). 2009 Aug-Sep;165(8-9):676-83
– reference: 16717206 - Neurology. 2006 May 23;66(10 ):1485-9
– reference: 15589308 - Lancet. 2004 Dec 11-17;364(9451):2106-12
– reference: 18283393 - J Neurol. 2008 May;255(5):710-5
– reference: 21967235 - Eur J Neurol. 2012 Apr;19(4):655-9
– reference: 17439988 - Brain. 2007 May;130(Pt 5):1206-23
– reference: 19465451 - Mult Scler. 2009 Jul;15(7):834-47
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Snippet Background. Neuromyelitis optica (Devic’s disease) is a severe autoimmune inflammatory disorder of the central nervous system. Epidemiological aspects of NMO...
Background. Neuromyelitis optica (Devic’s disease) is a severe autoimmune inflammatory disorder of the central nervous system. Epidemiological aspects of NMO...
Background. Neuromyelitis optica (Devic's disease) is a severe autoimmune inflammatory disorder of the central nervous system. Epidemiological aspects of NMO...
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SubjectTerms Data collection
Diagnosis
Epidemiology
Estimates
Meta-analysis
Multiple sclerosis
Neuromyelitis optica
Prevalence studies (Epidemiology)
Quality
Review
Spinal cord
Studies
Systematic review
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Title Epidemiology of Neuromyelitis Optica in the World: A Systematic Review and Meta-Analysis
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