Pooling designs and nonadaptive group testing important tools for DNA sequencing.

Pooling designs have been widely used in various aspects of DNA sequencing. In biological applications, the well-studied mathematical problem called “group testing” shifts its focus to nonadaptive algorithms while the focus of traditional group testing is on sequential algorithms. Biological applica...

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Bibliographic Details
Main Authors: Du, Dingzhu, Hwang, Frank K
Format: eBook Book
Language:English
Published: New Jersey World Scientific Publishing Co. Pte. Ltd 2006
World Scientific
World Scientific Publishing Company
WORLD SCIENTIFIC
WSPC
Series:Series on applied mathematics
Subjects:
Bioinformatics and Computational Biology
BioMathematics
Biostatistics
Combinatorial group theory
Molecular biology
Molecular biology > Mathematics
Nucleotide sequence
Nucleotide sequence > Mathematics
SCIENCE
Clone Library Screening
Disjunct Matrix
Pooling Designs
Group Testing
DNA Sequencing
Physical Mapping
ISBN:9789812568229, 9789812773463, 9812773460, 9812568220
Online Access:Get full text
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Table of Contents:
  • Pooling designs and nonadaptive group testing : important tools for DNA sequencing -- Preface -- Contents -- 1. Introduction -- 2. Basic Theory on Separating Matrices -- 3. Deterministic Designs -- 4. Deterministic Designs from Partial Orders -- 5. Random Pooling Designs and Probabilistic Analysis -- 6. Pooling Designs on Complexes -- 7. Contig Sequencing -- 8. The Inhibitor Model -- 9. Hyperplane Designs -- 10. Non-unique Probe Selection -- Index -- Back Cover