Absolute Quantitative MALDI Imaging Mass Spectrometry: A Case of Rifampicin in Liver Tissues

Matrix-assisted laser desorption/ionization (MALDI) imaging mass spectrometry (IMS) elucidates molecular distributions in thin tissue sections. Absolute pixel-to-pixel quantitation has remained a challenge, primarily lacking validation of the appropriate analytical methods. In the present work, isot...

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Bibliographic Details

Published in:	Analytical chemistry (Washington) Vol. 88; no. 4; pp. 2392 - 2398
Main Authors:	Chumbley, Chad W, Reyzer, Michelle L, Allen, Jamie L, Marriner, Gwendolyn A, Via, Laura E, Barry, 3rd, Clifton E, Caprioli, Richard M
Format:	Journal Article
Language:	English
Published:	United States 16.02.2016
Subjects:	Animals Chromatography, High Pressure Liquid Liver - chemistry Rats Rifampin - analysis Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization
ISSN:	1520-6882
Online Access:	Get more information
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