MALDI-FTICR imaging mass spectrometry of drugs and metabolites in tissue

A new approach is described for imaging mass spectrometry analysis of drugs and metabolites in tissue using matrix-assisted laser desorption ionization-Fourier transform ion cyclotron resonance (MALDI-FTICR). The technique utilizes the high resolving power to produce images from thousands of ions me...

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Vydané v:	Analytical chemistry (Washington) Ročník 80; číslo 14; s. 5648
Hlavní autori:	Cornett, Dale S, Frappier, Sara L, Caprioli, Richard M
Médium:	Journal Article
Jazyk:	English
Vydavateľské údaje:	United States 15.07.2008
Predmet:	Animals Fluorescence Resonance Energy Transfer - methods Liver - metabolism Male Mice Molecular Structure Pharmaceutical Preparations - analysis Pharmaceutical Preparations - chemistry Pharmaceutical Preparations - metabolism Rats Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization - methods
ISSN:	1520-6882, 1520-6882
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