MALDI-FTICR imaging mass spectrometry of drugs and metabolites in tissue

A new approach is described for imaging mass spectrometry analysis of drugs and metabolites in tissue using matrix-assisted laser desorption ionization-Fourier transform ion cyclotron resonance (MALDI-FTICR). The technique utilizes the high resolving power to produce images from thousands of ions me...

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Bibliographic Details

Published in:	Analytical chemistry (Washington) Vol. 80; no. 14; p. 5648
Main Authors:	Cornett, Dale S, Frappier, Sara L, Caprioli, Richard M
Format:	Journal Article
Language:	English
Published:	United States 15.07.2008
Subjects:	Animals Fluorescence Resonance Energy Transfer - methods Liver - metabolism Male Mice Molecular Structure Pharmaceutical Preparations - analysis Pharmaceutical Preparations - chemistry Pharmaceutical Preparations - metabolism Rats Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization - methods
ISSN:	1520-6882, 1520-6882
Online Access:	Get more information
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