An adoption study of parental depression as an environmental liability for adolescent depression and childhood disruptive disorders

The authors used an adoption study design to investigate environmental influences on risk for psychopathology in adolescents with depressed parents. Participants were 568 adopted adolescents ascertained through large adoption agencies, 416 nonadopted adolescents ascertained through birth records, an...

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Vydáno v:	The American journal of psychiatry Ročník 165; číslo 9; s. 1148
Hlavní autoři:	Tully, Erin C, Iacono, William G, McGue, Matt
Médium:	Journal Article
Jazyk:	angličtina
Vydáno:	United States 01.09.2008
Témata:	Adolescent Adult Attention Deficit and Disruptive Behavior Disorders - epidemiology Attention Deficit and Disruptive Behavior Disorders - psychology Child of Impaired Parents - psychology Child of Impaired Parents - statistics & numerical data Depressive Disorder, Major - diagnosis Depressive Disorder, Major - epidemiology Depressive Disorder, Major - psychology Diagnostic and Statistical Manual of Mental Disorders Fathers - psychology Female Humans Male Parents - psychology Prevalence Risk Factors Severity of Illness Index Social Environment
ISSN:	1535-7228, 1535-7228
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Shrnutí:	The authors used an adoption study design to investigate environmental influences on risk for psychopathology in adolescents with depressed parents. Participants were 568 adopted adolescents ascertained through large adoption agencies, 416 nonadopted adolescents ascertained through birth records, and their parents. Clinical interviews with parents and adolescents were used to determine lifetime DSM-IV-TR diagnoses of major depressive disorder, oppositional defiant disorder, conduct disorder, attention deficit hyperactivity disorder (ADHD), and substance use disorders in adolescents and major depression in mothers and fathers. Effects of parental depression (either parent with major depression, maternal major depression, and paternal major depression) on adolescent psychopathology were tested in nonadopted and adopted adolescents separately, and interactive effects of parental depression and adoption status were tested. Either parent having major depression and a mother having major depression were associated with a significantly greater risk for major depression and disruptive behavior disorders in both nonadopted and adopted adolescents. Paternal depression did not have a main effect on any psychiatric disorder in adolescents and, with one exception (ADHD in adopted adolescents), did not predict significantly greater likelihoods of disorders in either nonadopted or adopted adolescents. Maternal depression was an environmental liability for lifetime diagnoses of major depression and disruptive disorders in adolescents. Paternal depression was not associated with an increased risk for psychopathology in adolescents.
Bibliografie:	ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23
ISSN:	1535-7228 1535-7228
DOI:	10.1176/appi.ajp.2008.07091438