Accurate Identification of Deamidation and Citrullination from Global Shotgun Proteomics Data Using a Dual-Search Delta Score Strategy

Proteins with deamidated/citrullinated amino acids play critical roles in the pathogenesis of many human diseases; however, identifying these modifications in complex biological samples has been an ongoing challenge. Herein we present a method to accurately identify these modifications from shotgun...

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Vydané v:	Journal of proteome research Ročník 19; číslo 4; s. 1863
Hlavní autori:	Wang, Xi, Swensen, Adam C, Zhang, Tong, Piehowski, Paul D, Gaffrey, Matthew J, Monroe, Matthew E, Zhu, Ying, Dong, Hailiang, Qian, Wei-Jun
Médium:	Journal Article
Jazyk:	English
Vydavateľské údaje:	United States 03.04.2020
Predmet:	deamidation dual search Delta Score citrullination shotgun proteomics
ISSN:	1535-3907, 1535-3907
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