Skin-Interfaced Wearable Sweat Sensors for Precision Medicine

Wearable sensors hold great potential in empowering personalized health monitoring, predictive analytics, and timely intervention toward personalized healthcare. Advances in flexible electronics, materials science, and electrochemistry have spurred the development of wearable sweat sensors that enab...

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Veröffentlicht in:Chemical reviews Jg. 123; H. 8; S. 5049
Hauptverfasser: Min, Jihong, Tu, Jiaobing, Xu, Changhao, Lukas, Heather, Shin, Soyoung, Yang, Yiran, Solomon, Samuel A, Mukasa, Daniel, Gao, Wei
Format: Journal Article
Sprache:Englisch
Veröffentlicht: United States 26.04.2023
Schlagworte:
Biosensing Techniques
Electronics
Monitoring, Physiologic
Precision Medicine
Skin
Sweat
Wearable Electronic Devices
ISSN:1520-6890, 1520-6890
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Zusammenfassung:Wearable sensors hold great potential in empowering personalized health monitoring, predictive analytics, and timely intervention toward personalized healthcare. Advances in flexible electronics, materials science, and electrochemistry have spurred the development of wearable sweat sensors that enable the continuous and noninvasive screening of analytes indicative of health status. Existing major challenges in wearable sensors include: improving the sweat extraction and sweat sensing capabilities, improving the form factor of the wearable device for minimal discomfort and reliable measurements when worn, and understanding the clinical value of sweat analytes toward biomarker discovery. This review provides a comprehensive review of wearable sweat sensors and outlines state-of-the-art technologies and research that strive to bridge these gaps. The physiology of sweat, materials, biosensing mechanisms and advances, and approaches for sweat induction and sampling are introduced. Additionally, design considerations for the system-level development of wearable sweat sensing devices, spanning from strategies for prolonged sweat extraction to efficient powering of wearables, are discussed. Furthermore, the applications, data analytics, commercialization efforts, challenges, and prospects of wearable sweat sensors for precision medicine are discussed.
Bibliographie:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
ObjectType-Review-3
content type line 23
ISSN:1520-6890
1520-6890
DOI:10.1021/acs.chemrev.2c00823