The Fanconi Anemia Pathway in Cancer

Fanconi anemia (FA) is a complex genetic disorder characterized by bone marrow failure (BMF), congenital defects, inability to repair DNA interstrand cross-links (ICLs), and cancer predisposition. FA presents two seemingly opposite characteristics: ( ) massive cell death of the hematopoietic stem an...

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Bibliographic Details

Published in:	Annual review of cancer biology Vol. 3; p. 457
Main Authors:	Niraj, Joshi, Färkkilä, Anniina, D'Andrea, Alan D
Format:	Journal Article
Language:	English
Published:	United States 04.03.2019
Subjects:	somatic cancer DNA interstrand cross-links Fanconi anemia genomic instability DNA repair
ISSN:	2472-3428, 2472-3428
Online Access:	Get more information
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