Optimization of spatiotemporally fractionated radiotherapy treatments with bounds on the achievable benefit

Spatiotemporal fractionation schemes, that is, treatments delivering different dose distributions in different fractions, may lower treatment side effects without compromising tumor control. This is achieved by hypofractionating parts of the tumor while delivering approximately uniformly fractionate...

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Veröffentlicht in:	arXiv.org
Hauptverfasser:	Gaddy, Melissa R, Sercan Yıldız, Unkelbach, Jan, Papp, Dávid
Format:	Paper
Sprache:	Englisch
Veröffentlicht:	Ithaca Cornell University Library, arXiv.org 08.12.2017
Schlagworte:	Biological effects Computational geometry Convexity Fractionation Liver Local optimization Lower bounds Quadratic programming Radiation therapy Reduction Semidefinite programming Side effects Tumors
ISSN:	2331-8422
Online-Zugang:	Volltext
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