Atlas-Based Interpretable Age Prediction In Whole-Body MR Images

Age prediction is an important part of medical assessments and research. It can aid in detecting diseases as well as abnormal ageing by highlighting potential discrepancies between chronological and biological age. To improve understanding of age-related changes in various body parts, we investigate...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:arXiv.org
Hlavní autoři: Starck, Sophie, Yadunandan Vivekanand Kini, Ritter, Jessica Johanna Maria, Braren, Rickmer, Rueckert, Daniel, Mueller, Tamara
Médium: Paper
Jazyk:angličtina
Vydáno: Ithaca Cornell University Library, arXiv.org 27.11.2024
Témata:
Age
Aging
Body parts
Investigations
ISSN:2331-8422
On-line přístup:Získat plný text
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo vytvoří štítek k tomuto záznamu!
Popis
Shrnutí:Age prediction is an important part of medical assessments and research. It can aid in detecting diseases as well as abnormal ageing by highlighting potential discrepancies between chronological and biological age. To improve understanding of age-related changes in various body parts, we investigate the ageing of the human body on a large scale by using whole-body 3D images. We utilise the Grad-CAM method to determine the body areas most predictive of a person's age. In order to expand our analysis beyond individual subjects, we employ registration techniques to generate population-wide importance maps that show the most predictive areas in the body for a whole cohort of subjects. We show that the investigation of the full 3D volume of the whole body and the population-wide analysis can give important insights into which body parts play the most important roles in predicting a person's age. Our findings reveal three primary areas of interest: the spine, the autochthonous back muscles, and the cardiac region, which exhibits the highest importance. Finally, we investigate differences between subjects that show accelerated and decelerated ageing.
Bibliografie:SourceType-Working Papers-1
ObjectType-Working Paper/Pre-Print-1
content type line 50
ISSN:2331-8422
DOI:10.48550/arxiv.2307.07439