A genetic atlas of human admixture history

Modern genetic data combined with appropriate statistical methods have the potential to contribute substantially to our understanding of human history. We have developed an approach that exploits the genomic structure of admixed populations to date and characterize historical mixture events at fine...

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Vydáno v:Science (American Association for the Advancement of Science) Ročník 343; číslo 6172; s. 747
Hlavní autoři: Hellenthal, Garrett, Busby, George B J, Band, Gavin, Wilson, James F, Capelli, Cristian, Falush, Daniel, Myers, Simon
Médium: Journal Article
Jazyk:angličtina
Vydáno: United States 14.02.2014
Témata:
Alleles
Chromosome Painting - methods
Computer Simulation
DNA - genetics
Europe, Eastern - ethnology
Genetic Drift
Genotyping Techniques
Haplotypes
History, Ancient
Human Migration - history
Humans
Middle East - ethnology
Models, Genetic
Mongolia - ethnology
Polymorphism, Single Nucleotide
Population - genetics
Software
Middle East
Europe, Eastern
Mongolia
ISSN:1095-9203, 1095-9203
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Shrnutí:Modern genetic data combined with appropriate statistical methods have the potential to contribute substantially to our understanding of human history. We have developed an approach that exploits the genomic structure of admixed populations to date and characterize historical mixture events at fine scales. We used this to produce an atlas of worldwide human admixture history, constructed by using genetic data alone and encompassing over 100 events occurring over the past 4000 years. We identified events whose dates and participants suggest they describe genetic impacts of the Mongol empire, Arab slave trade, Bantu expansion, first millennium CE migrations in Eastern Europe, and European colonialism, as well as unrecorded events, revealing admixture to be an almost universal force shaping human populations.
Bibliografie:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
ISSN:1095-9203
1095-9203
DOI:10.1126/science.1243518