Spatial Metabolomics of the Human Kidney using MALDI Trapped Ion Mobility Imaging Mass Spectrometry

Low molecular weight metabolites are essential for defining the molecular phenotypes of cells. However, spatial metabolomics tools often lack the sensitivity, specify, and spatial resolution to provide comprehensive descriptions of these species in tissue. MALDI imaging mass spectrometry (IMS) of lo...

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Veröffentlicht in:	Analytical chemistry (Washington) Jg. 92; H. 19; S. 13084
Hauptverfasser:	Neumann, Elizabeth K, Migas, Lukasz G, Allen, Jamie L, Caprioli, Richard M, Van de Plas, Raf, Spraggins, Jeffrey M
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	United States 06.10.2020
Schlagworte:	Acetylcarnitine - analysis Acetylcarnitine - metabolism Arginine - analogs & derivatives Arginine - analysis Arginine - metabolism Choline - analysis Choline - metabolism Humans Ion Mobility Spectrometry Kidney - chemistry Kidney - metabolism Metabolomics Molecular Weight Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization
ISSN:	1520-6882, 1520-6882
Online-Zugang:	Weitere Angaben
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