Apollo: A Sequencing-Technology-Independent, Scalable, and Accurate Assembly Polishing Algorithm

Long reads produced by third-generation sequencing technologies are used to construct an assembly (i.e., the subject's genome), which is further used in downstream genome analysis. Unfortunately, long reads have high sequencing error rates and a large proportion of bps in these long reads are i...

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Veröffentlicht in:	arXiv.org
Hauptverfasser:	Firtina, Can, Kim, Jeremie S, Alser, Mohammed, Cali, Damla Senol, Cicek, A Ercument, Alkan, Can, Mutlu, Onur
Format:	Paper
Sprache:	Englisch
Veröffentlicht:	Ithaca Cornell University Library, arXiv.org 07.03.2020
Schlagworte:	Algorithms Alignment Assemblies Assembly Dependence Error analysis Gene sequencing Genomes Markov chains Polishes Polishing State of the art Viterbi algorithm detectors
ISSN:	2331-8422
Online-Zugang:	Volltext
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