Importance of Nucleic Acid Recognition in Inflammation and Autoimmunity

An important concept in immunology is the classification of immune responses as either innate or adaptive, based on whether the antigen receptors are encoded in the germline or generated somatically by gene rearrangement. The innate immune system is an ancient mode of immunity, and by being a first...

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Bibliographic Details
Published in:	Annual review of medicine Vol. 67; p. 323
Main Authors:	Barrat, Franck J, Elkon, Keith B, Fitzgerald, Katherine A
Format:	Journal Article
Language:	English
Published:	United States 14.01.2016
Subjects:	Adjuvants, Immunologic - therapeutic use Aminoquinolines - therapeutic use Animals Autoimmunity - immunology Cytosol - immunology DNA, Viral - immunology Endosomes - immunology Humans Imiquimod Immunity, Innate Inflammation - immunology Inflammation - metabolism Lupus Erythematosus, Systemic - immunology Nucleic Acids - immunology Psoriasis - immunology Signal Transduction Toll-Like Receptors - agonists Toll-Like Receptors - antagonists & inhibitors Toll-Like Receptors - immunology Virus Diseases - immunology pattern recognition receptors therapeutics nucleic acids autoimmunity innate immunity
ISSN:	1545-326X, 1545-326X
Online Access:	Get more information
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