Site-Selective Aliphatic C-H Chlorination Using N-Chloroamides Enables a Synthesis of Chlorolissoclimide

Methods for the practical, intermolecular functionalization of aliphatic C-H bonds remain a paramount goal of organic synthesis. Free radical alkane chlorination is an important industrial process for the production of small molecule chloroalkanes from simple hydrocarbons, yet applications to fine c...

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Bibliographic Details
Published in:Journal of the American Chemical Society Vol. 138; no. 2; pp. 696 - 702
Main Authors: Quinn, Ryan K., Koenst, Zef A., Michalak, Sharon E., Schmidt, Yvonne, Szklarski, Anne R., Flores, Alex R., Nam, Sangkil, Horne, David A., Vanderwal, Christopher D., Alexanian, Erik J.
Format: Journal Article
Language:English
Published: WASHINGTON Amer Chemical Soc 20.01.2016
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ISSN:0002-7863, 1520-5126, 1520-5126
Online Access:Get more information
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