Aminoglycoside Antibiotics Inhibit Phage Infection by Blocking an Early Step of the Infection Cycle

Predation by phages is a major driver of bacterial evolution. As a result, elucidating antiphage strategies is crucial from both fundamental and therapeutic standpoints. In response to viral predation, bacteria have evolved a wide range of defense mechanisms, which rely mostly on proteins acting at...

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Vydané v:	mBio Ročník 13; číslo 3; s. e0078322
Hlavní autori:	Kever, Larissa, Hardy, Aël, Luthe, Tom, Hünnefeld, Max, Gätgens, Cornelia, Milke, Lars, Wiechert, Johanna, Wittmann, Johannes, Moraru, Cristina, Marienhagen, Jan, Frunzke, Julia
Médium:	Journal Article
Jazyk:	English
Vydavateľské údaje:	United States American Society for Microbiology 28.06.2022
Predmet:	Acetylation Aminoglycoside antibiotics aminoglycosides Antibacterial activity Antibiotics Antiviral activity Apramycin Bacteria bacteriophages CRISPR Defense mechanisms E coli Genomes Host-Microbial Interactions Infections Metabolites phage defense phage-host interaction Phages Predation Protein biosynthesis Research Article Restriction-modification Streptomyces Translation Streptomyces aminoglycosides phage defense phage-host interaction antibiotics bacteriophages
ISSN:	2150-7511, 2161-2129, 2150-7511
On-line prístup:	Získať plný text
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