The Genetic Architecture of Obsessive-Compulsive Disorder: Contribution of Liability to OCD From Alleles Across the Frequency Spectrum

Obsessive-compulsive disorder (OCD) is known to be substantially heritable; however, the contribution of genetic variation across the allele frequency spectrum to this heritability remains uncertain. The authors used two new homogeneous cohorts to estimate the heritability of OCD from inherited gene...

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Bibliographic Details

Published in:	The American journal of psychiatry Vol. 179; no. 3; p. 216
Main Authors:	Mahjani, Behrang, Klei, Lambertus, Mattheisen, Manuel, Halvorsen, Matthew W, Reichenberg, Abraham, Roeder, Kathryn, Pedersen, Nancy L, Boberg, Julia, de Schipper, Elles, Bulik, Cynthia M, Landén, Mikael, Fundín, Bengt, Mataix-Cols, David, Sandin, Sven, Hultman, Christina M, Crowley, James J, Buxbaum, Joseph D, Rück, Christian, Devlin, Bernie, Grice, Dorothy E
Format:	Journal Article
Language:	English
Published:	United States 01.03.2022
Subjects:	Alleles Genome-Wide Association Study - methods Humans Multifactorial Inheritance Obsessive-Compulsive Disorder - diagnosis Obsessive-Compulsive Disorder - genetics Polymorphism, Single Nucleotide - genetics Obsessive-Compulsive Disorder Genetics Heritability
ISSN:	1535-7228, 1535-7228
Online Access:	Get more information
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