The Genetic Architecture of Obsessive-Compulsive Disorder: Contribution of Liability to OCD From Alleles Across the Frequency Spectrum

Obsessive-compulsive disorder (OCD) is known to be substantially heritable; however, the contribution of genetic variation across the allele frequency spectrum to this heritability remains uncertain. The authors used two new homogeneous cohorts to estimate the heritability of OCD from inherited gene...

Celý popis

Podrobná bibliografie

Vydáno v:	The American journal of psychiatry Ročník 179; číslo 3; s. 216
Hlavní autoři:	Mahjani, Behrang, Klei, Lambertus, Mattheisen, Manuel, Halvorsen, Matthew W, Reichenberg, Abraham, Roeder, Kathryn, Pedersen, Nancy L, Boberg, Julia, de Schipper, Elles, Bulik, Cynthia M, Landén, Mikael, Fundín, Bengt, Mataix-Cols, David, Sandin, Sven, Hultman, Christina M, Crowley, James J, Buxbaum, Joseph D, Rück, Christian, Devlin, Bernie, Grice, Dorothy E
Médium:	Journal Article
Jazyk:	angličtina
Vydáno:	United States 01.03.2022
Témata:	Alleles Genome-Wide Association Study - methods Humans Multifactorial Inheritance Obsessive-Compulsive Disorder - diagnosis Obsessive-Compulsive Disorder - genetics Polymorphism, Single Nucleotide - genetics Obsessive-Compulsive Disorder Genetics Heritability
ISSN:	1535-7228, 1535-7228
On-line přístup:	Zjistit podrobnosti o přístupu
Tagy:	Přidat tag Žádné tagy, Buďte první, kdo vytvoří štítek k tomuto záznamu!