Mapping Microbial Response Metabolomes for Induced Natural Product Discovery

Intergeneric microbial interactions may originate a significant fraction of secondary metabolic gene regulation in nature. Herein, we expose a genomically characterized Nocardiopsis strain, with untapped polyketide biosynthetic potential, to intergeneric interactions via coculture with low inoculum...

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Bibliographic Details

Published in:	ACS chemical biology Vol. 10; no. 9; pp. 1998 - 2006
Main Authors:	Derewacz, Dagmara K, Covington, Brett C, McLean, John A, Bachmann, Brian O
Format:	Journal Article
Language:	English
Published:	United States 18.09.2015
Subjects:	Actinomycetales - metabolism Aminoglycosides - metabolism Bacillus subtilis - metabolism Biological Products - metabolism Coculture Techniques Escherichia coli - metabolism Lactams - metabolism Macrolides - metabolism Metabolome Metabolomics Polyketides - metabolism Rhodococcus - metabolism
ISSN:	1554-8937
Online Access:	Get more information
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