Calcium Signaling Mechanisms Across Kingdoms
Calcium (Ca ) is a unique mineral that serves as both a nutrient and a signal in all eukaryotes. To maintain Ca homeostasis for both nutrition and signaling purposes, the tool kit for Ca transport has expanded across kingdoms of eukaryotes to encode specific Ca signals referred to as Ca signatures....
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| Published in: | Annual review of cell and developmental biology Vol. 37; p. 311 |
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| Main Authors: | , |
| Format: | Journal Article |
| Language: | English |
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United States
06.10.2021
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| ISSN: | 1530-8995, 1530-8995 |
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| Abstract | Calcium (Ca
) is a unique mineral that serves as both a nutrient and a signal in all eukaryotes. To maintain Ca
homeostasis for both nutrition and signaling purposes, the tool kit for Ca
transport has expanded across kingdoms of eukaryotes to encode specific Ca
signals referred to as Ca
signatures. In parallel, a large array of Ca
-binding proteins has evolved as specific sensors to decode Ca
signatures. By comparing these coding and decoding mechanisms in fungi, animals, and plants, both unified and divergent themes have emerged, and the underlying complexity will challenge researchers for years to come. Considering the scale and breadth of the subject, instead of a literature survey, in this review we focus on a conceptual framework that aims to introduce readers to the principles and mechanisms of Ca
signaling. We finish with several examples of Ca
-signaling pathways, including polarized cell growth, immunity and symbiosis, and systemic signaling, to piece together specific coding and decoding mechanisms in plants versus animals. |
|---|---|
| AbstractList | Calcium (Ca
) is a unique mineral that serves as both a nutrient and a signal in all eukaryotes. To maintain Ca
homeostasis for both nutrition and signaling purposes, the tool kit for Ca
transport has expanded across kingdoms of eukaryotes to encode specific Ca
signals referred to as Ca
signatures. In parallel, a large array of Ca
-binding proteins has evolved as specific sensors to decode Ca
signatures. By comparing these coding and decoding mechanisms in fungi, animals, and plants, both unified and divergent themes have emerged, and the underlying complexity will challenge researchers for years to come. Considering the scale and breadth of the subject, instead of a literature survey, in this review we focus on a conceptual framework that aims to introduce readers to the principles and mechanisms of Ca
signaling. We finish with several examples of Ca
-signaling pathways, including polarized cell growth, immunity and symbiosis, and systemic signaling, to piece together specific coding and decoding mechanisms in plants versus animals. Calcium (Ca2+) is a unique mineral that serves as both a nutrient and a signal in all eukaryotes. To maintain Ca2+ homeostasis for both nutrition and signaling purposes, the tool kit for Ca2+ transport has expanded across kingdoms of eukaryotes to encode specific Ca2+ signals referred to as Ca2+ signatures. In parallel, a large array of Ca2+-binding proteins has evolved as specific sensors to decode Ca2+ signatures. By comparing these coding and decoding mechanisms in fungi, animals, and plants, both unified and divergent themes have emerged, and the underlying complexity will challenge researchers for years to come. Considering the scale and breadth of the subject, instead of a literature survey, in this review we focus on a conceptual framework that aims to introduce readers to the principles and mechanisms of Ca2+ signaling. We finish with several examples of Ca2+-signaling pathways, including polarized cell growth, immunity and symbiosis, and systemic signaling, to piece together specific coding and decoding mechanisms in plants versus animals.Calcium (Ca2+) is a unique mineral that serves as both a nutrient and a signal in all eukaryotes. To maintain Ca2+ homeostasis for both nutrition and signaling purposes, the tool kit for Ca2+ transport has expanded across kingdoms of eukaryotes to encode specific Ca2+ signals referred to as Ca2+ signatures. In parallel, a large array of Ca2+-binding proteins has evolved as specific sensors to decode Ca2+ signatures. By comparing these coding and decoding mechanisms in fungi, animals, and plants, both unified and divergent themes have emerged, and the underlying complexity will challenge researchers for years to come. Considering the scale and breadth of the subject, instead of a literature survey, in this review we focus on a conceptual framework that aims to introduce readers to the principles and mechanisms of Ca2+ signaling. We finish with several examples of Ca2+-signaling pathways, including polarized cell growth, immunity and symbiosis, and systemic signaling, to piece together specific coding and decoding mechanisms in plants versus animals. |
| Author | Wang, Chao Luan, Sheng |
| Author_xml | – sequence: 1 givenname: Sheng surname: Luan fullname: Luan, Sheng email: sluan@berkeley.edu organization: Department of Plant and Microbial Biology, University of California, Berkeley, California 94720, USA; email: sluan@berkeley.edu – sequence: 2 givenname: Chao surname: Wang fullname: Wang, Chao email: sluan@berkeley.edu organization: Department of Plant and Microbial Biology, University of California, Berkeley, California 94720, USA; email: sluan@berkeley.edu |
| BackLink | https://www.ncbi.nlm.nih.gov/pubmed/34375534$$D View this record in MEDLINE/PubMed |
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| Keywords | protein kinases polarized cell growth innate immunity calcium channels systemic signaling calcium-binding proteins |
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| Snippet | Calcium (Ca
) is a unique mineral that serves as both a nutrient and a signal in all eukaryotes. To maintain Ca
homeostasis for both nutrition and signaling... Calcium (Ca2+) is a unique mineral that serves as both a nutrient and a signal in all eukaryotes. To maintain Ca2+ homeostasis for both nutrition and signaling... |
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| Title | Calcium Signaling Mechanisms Across Kingdoms |
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