Derivation, Validation, and Potential Treatment Implications of Novel Clinical Phenotypes for Sepsis

Sepsis is a heterogeneous syndrome. Identification of distinct clinical phenotypes may allow more precise therapy and improve care. To derive sepsis phenotypes from clinical data, determine their reproducibility and correlation with host-response biomarkers and clinical outcomes, and assess the pote...

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Vydáno v:	JAMA : the journal of the American Medical Association Ročník 321; číslo 20; s. 2003
Hlavní autoři:	Seymour, Christopher W, Kennedy, Jason N, Wang, Shu, Chang, Chung-Chou H, Elliott, Corrine F, Xu, Zhongying, Berry, Scott, Clermont, Gilles, Cooper, Gregory, Gomez, Hernando, Huang, David T, Kellum, John A, Mi, Qi, Opal, Steven M, Talisa, Victor, van der Poll, Tom, Visweswaran, Shyam, Vodovotz, Yoram, Weiss, Jeremy C, Yealy, Donald M, Yende, Sachin, Angus, Derek C
Médium:	Journal Article
Jazyk:	angličtina
Vydáno:	United States 28.05.2019
Témata:	Algorithms Biomarkers - blood Cluster Analysis Datasets as Topic Hospital Mortality Humans Machine Learning Organ Dysfunction Scores Phenotype Reproducibility of Results Retrospective Studies Sepsis - classification Sepsis - mortality Sepsis - therapy
ISSN:	1538-3598, 1538-3598
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