Derivation, Validation, and Potential Treatment Implications of Novel Clinical Phenotypes for Sepsis

Sepsis is a heterogeneous syndrome. Identification of distinct clinical phenotypes may allow more precise therapy and improve care. To derive sepsis phenotypes from clinical data, determine their reproducibility and correlation with host-response biomarkers and clinical outcomes, and assess the pote...

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Bibliographic Details

Published in:	JAMA : the journal of the American Medical Association Vol. 321; no. 20; p. 2003
Main Authors:	Seymour, Christopher W, Kennedy, Jason N, Wang, Shu, Chang, Chung-Chou H, Elliott, Corrine F, Xu, Zhongying, Berry, Scott, Clermont, Gilles, Cooper, Gregory, Gomez, Hernando, Huang, David T, Kellum, John A, Mi, Qi, Opal, Steven M, Talisa, Victor, van der Poll, Tom, Visweswaran, Shyam, Vodovotz, Yoram, Weiss, Jeremy C, Yealy, Donald M, Yende, Sachin, Angus, Derek C
Format:	Journal Article
Language:	English
Published:	United States 28.05.2019
Subjects:	Algorithms Biomarkers - blood Cluster Analysis Datasets as Topic Hospital Mortality Humans Machine Learning Organ Dysfunction Scores Phenotype Reproducibility of Results Retrospective Studies Sepsis - classification Sepsis - mortality Sepsis - therapy
ISSN:	1538-3598, 1538-3598
Online Access:	Get more information
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