Role of translocator protein density, a marker of neuroinflammation, in the brain during major depressive episodes

The neuroinflammatory hypothesis of major depressive disorder is supported by several main findings. First, in humans and animals, activation of the immune system causes sickness behaviors that present during a major depressive episode (MDE), such as low mood, anhedonia, anorexia, and weight loss. S...

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Bibliographic Details
Published in:	JAMA psychiatry (Chicago, Ill.) Vol. 72; no. 3; p. 268
Main Authors:	Setiawan, Elaine, Wilson, Alan A, Mizrahi, Romina, Rusjan, Pablo M, Miler, Laura, Rajkowska, Grazyna, Suridjan, Ivonne, Kennedy, James L, Rekkas, P Vivien, Houle, Sylvain, Meyer, Jeffrey H
Format:	Journal Article
Language:	English
Published:	United States 01.03.2015
Subjects:	Adult Anilides Biomarkers - metabolism Case-Control Studies Cerebral Cortex - metabolism Depressive Disorder, Major - metabolism Female Gyrus Cinguli - metabolism Humans Inflammation - metabolism Male Microglia - metabolism Middle Aged Positron-Emission Tomography - methods Prefrontal Cortex - metabolism Pyridines Receptors, GABA - metabolism Severity of Illness Index
ISSN:	2168-6238, 2168-6238
Online Access:	Get more information
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